samedi 9 juin 2012
Heures | événement | (+) |
09:30 - 09:50 | Overview and short history of repeat expansion diseases - Jean-Louis Mandel, IGBMC | |
09:50 - 10:25 | Mechanisms of repeat instability - Christopher Pearson, Hospital for Sick Children/Canada | |
10:25 - 11:00 | SBMA (spinobulbar muscular atrophy): from gene discovery to mechanism and treatment - Kurt Fischbeck, NIH/USA | |
11:00 - 11:15 | Pause café | |
11:15 - 11:50 | Animal models for Fragile X syndrome and FXTAS: What have they taught us, current and future developments. - Ben Oostra, Erasmus University/The Netherlands | |
11:50 - 12:25 | 20 years of anticipation: from mutation to therapy - Keith Johnson, Novartis/USA | |
12:25 - 13:00 | Friedreich ataxia: from GAA repeats to pathomechanisms and therapeutic prospects - Michel Koenig & Helene Puccio, IGBMC | |
13:00 - 14:00 | Déjeuner | |
14:00 - 14:35 | Overview of current clinical trials in Europe for HD, polyglutamine SCAs (spinocerebellar ataxias) and Friedreich ataxia - Alexandra Durr, Hopital Pitié Salpétrière/ICM/France | |
14:35 - 15:10 | Unexpected mechanisms (antisense transcripts, RAN translation) - Laura Ranum, University of Florida/USA | |
15:10 - 15:45 | Toxic mRNAs mechanisms in myotonic dystrophies and in Fragile X tremor ataxia syndrome (FXTAS) - Nicolas Charlet, IGBMC | |
15:45 - 15:55 | Pause café | |
15:55 - 16:20 | Use of human embryonic stem cells for development of novel therapeutic strategies in Myotonic Dystrophy Type 1 and in Huntington disease. - Cécile Martinat, I-STEM/France | |
16:20 - 16:40 | Perspectives of treatment with antisense oligos in Myotonic Dystrophy. - Denis Furling, Institut de Myologie/France |